Cystic Fibrosis | American Academy of Pediatrics - AAP News

Cystic Fibrosis | American Academy of Pediatrics - AAP News

Cystic Fibrosis | American Academy of Pediatrics - AAP News

Posted: 01 Feb 2021 12:00 AM PST

  1. Kimberly M. Dickinson, MD, MPH*
  2. Joseph M. Collaco, MD, PhD*
  1. *Eudowood Division of Pediatric Respiratory Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD

Abstract

Cystic fibrosis (CF) is one of the most commonly diagnosed genetic disorders. Clinical characteristics include progressive obstructive lung disease, sinusitis, exocrine pancreatic insufficiency leading to malabsorption and malnutrition, liver and pancreatic dysfunction, and male infertility. Although CF is a life-shortening disease, survival has continued to improve to a median age of 46.2 years due to earlier diagnosis through routine newborn screening, promulgation of evidence-based guidelines to optimize nutritional and pulmonary health, and the development of CF-specific interdisciplinary care centers. Future improvements in health and quality of life for individuals with CF are likely with the recent development of mutation-specific modulator therapies. In this review, we will cover the current understanding of the disease manifestations, diagnosis, and management as well as common complications seen in individuals with CF.
-

Comments

Post a Comment

Popular Posts

Community-Acquired Pneumonia: Symptoms and Treatment - Verywell Health

Image
There are several ways that you can develop pneumonia ranging from inhaling toxic substances in the workplace to unknowingly being infected by a bacteria in the hospital. Any lung infection acquired outside of the hospital setting is considered community-acquired pneumonia (CAP). Viruses and certain bacteria such as streptococcus pneumoniae (S. pneumoniae), haemophilus influenzae, and atypical bacteria—like chlamydia pneumoniae, mycoplasma pneumoniae, and Legionella species—are among the most common culprits of CAP. This article discusses the symptoms, causes, treatment, and prognosis for community-acquired pneumonia. Mongkol Chuewong / Getty Images Symptoms The clinical presentation of CAP varies wildly depending on the range. For example: Mild pneumonia is characterized by fever and a productive cough. Severe pneumonia is characterized by difficulty breathing and sepsis. Symptoms of CAP often develop quickly and are ac
Read more

How to Decode Your Baby's Cough - Yahoo Lifestyle

Image
How to Decode Your Baby's Cough - Yahoo Lifestyle How to Decode Your Baby's Cough - Yahoo Lifestyle Posted: 09 Apr 2013 12:00 AM PDT A baby's cough can mean many different things, and it's not as if you can ask your baby what's wrong. Sometimes it's hard to know if you should call your doctor for advice, make an appointment, or head straight to the emergency room . Coughs are the body's way of protecting itself, explains Howard Balbi, M.D., director of pediatric infectious diseases at Nassau County Medical Center in East Meadow, New York. Coughing serves as the method the body uses to keep the airways clear, ridding the throat of phlegm, postnasal drip (nasal mucus that drips down the back of the throat), or a lodged piece of food. There are two kinds of coughs that serve this purpose: dry cough and wet cough.  Baby Dry Cough: This occurs when a baby has a cold or allergies. A dry cough helps cle
Read more